Neuroimaging in genetic frontotemporal dementia and amyotrophic lateral sclerosis

Neuroimaging in genetic frontotemporal dementia and amyotrophic lateral sclerosis

Blog Article

Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) have a strong clinical, genetic truvisionhealthftp.com and pathological overlap.This review focuses on the current understanding of structural, functional and molecular neuroimaging signatures of genetic FTD and ALS.We overview quantitative neuroimaging studies on the most common genes associated with FTD valhalla axys (MAPT, GRN), ALS (SOD1), and both (C9orf72), and summarize visual observations of images reported in the rarer genes (CHMP2B, TARDBP, FUS, OPTN, VCP, UBQLN2, SQSTM1, TREM2, CHCHD10, TBK1).